Why Sleep Changes During Perimenopause
The Doctor’s Note Series
The Doctor’s Note Series provides physician insight into the most common questions women have about perimenopause and midlife wellness.
These articles are designed to help women better understand their bodies and support their health during hormonal transitions.
The Doctor’s Note Series provides physician insights on:
• Perimenopause and metabolism
• Hormonal health and midlife wellness
• Breast cancer prevention
• Skin and hair changes during hormonal transitions
• Women’s health and longevity
Read Doctor’s Note Below
Why Sleep Changes During Perimenopause:
Understanding Midlife Sleep Disruption
By April Spencer, M.D.
Many women notice sleep disruption during their 40s.
They may experience:
• Nighttime awakenings
• Difficulty falling asleep
• Early morning waking
• Restless sleep
These changes often coincide with perimenopause.
How Hormones Affect Sleep
Estrogen and progesterone influence neurotransmitters involved in sleep.
These hormones affect:
• Melatonin production
• Stress hormones
• Body temperature regulation
When hormone levels fluctuate, sleep quality can decline.
Why Sleep Matters for Metabolism
Poor sleep influences:
• Appetite hormones
• Blood sugar regulation
• Stress hormones
• Energy levels
Protecting sleep helps support metabolic and mental wellness.
Frequently Asked Questions
Why do women wake up at night during perimenopause?
Hormonal fluctuations can disrupt temperature regulation and sleep cycles.
Does estrogen affect sleep?
Yes. Estrogen influences neurotransmitters that regulate sleep patterns.
Can poor sleep cause weight gain?
Sleep disruption can affect appetite hormones and metabolism.
How can women improve sleep?
Consistent sleep schedules and stress management help support sleep quality.
About the Author
April Spencer, M.D. is a board-certified breast surgeon, mother of two, and the founder of Dr. Spencer’s Global Breast Health & Wellness Center.
With more than two decades of experience caring for women with breast cancer, Dr. Spencer is dedicated to advancing prevention, education, and proactive wellness strategies that empower women to take control of their health long before disease develops.
She is also the creator of Taylor Made RX Cosmetics, a physician-guided wellness and beauty brand developed to support women’s health from the inside out through targeted supplements, skincare, and hair care solutions designed for the unique needs of women navigating midlife and hormonal transitions.
Dr. Spencer’s work integrates medicine, prevention, and wellness to help women live healthier, more vibrant lives at every stage.
Explore the Doctor’s Note Series
The Doctor’s Note Series provides physician insights on:
• Perimenopause and metabolism
• Hormonal health and midlife wellness
• Breast cancer prevention
• Skin and hair changes during hormonal transitions
• Women’s health and longevity