Perimenopause Skin Changes

The Doctor’s Note Series

The Doctor’s Note Series provides physician insight into the most common questions women have about perimenopause and midlife wellness.

These articles are designed to help women better understand their bodies and support their health during hormonal transitions.

The Doctor’s Note Series provides physician insights on:
• Perimenopause and metabolism
• Hormonal health and midlife wellness
• Breast cancer prevention
• Skin and hair changes during hormonal transitions
• Women’s health and longevity

Read Doctor’s Note Below

Perimenopause Skin Changes:

Why Skin Becomes Drier and Less Elastic in Your 40s

By April Spencer, M.D.

Many women notice unexpected changes in their skin during midlife.

These changes may include:
• Increased dryness
• Fine lines
• Reduced elasticity
• Slower skin recovery

These shifts are often related to hormonal changes during perimenopause.

Skin becomes drier and less elastic during perimenopause
Why skin changes during perimenopause

Why Skin Changes During Perimenopause

Estrogen plays a critical role in maintaining skin health.

It supports:
• Collagen production
• Hydration
• Elasticity
• Skin thickness

As estrogen declines, the skin can become thinner and drier.

Collagen Loss in Midlife

Research suggests women may lose up to 30% of their skin collagen in the first five years around menopause.

This contributes to visible changes in skin texture and elasticity.

Collagen loss in midlife
Supporting skin health during midlife

Supporting Skin Health During Midlife

Strategies include:
• Hydration
• Antioxidant support
• Sun protection
• Targeted skincare

Supporting the skin internally and externally helps maintain skin vitality.

Frequently Asked Questions

Why does skin become drier in perimenopause?
Declining estrogen reduces the skin’s ability to retain moisture.

Does menopause affect collagen?
Yes. Estrogen helps support collagen production, which declines during menopause.

Why do wrinkles appear faster in midlife?
Reduced collagen and skin elasticity contribute to faster wrinkle formation.

How can women support skin health?
Hydration, antioxidant support, and protective skincare routines can help.

About the Author

April Spencer, M.D. is a board-certified breast surgeon, mother of two, and the founder of Dr. Spencer’s Global Breast Health & Wellness Center.

With more than two decades of experience caring for women with breast cancer, Dr. Spencer is dedicated to advancing prevention, education, and proactive wellness strategies that empower women to take control of their health long before disease develops.

She is also the creator of Taylor Made RX Cosmetics, a physician-guided wellness and beauty brand developed to support women’s health from the inside out through targeted supplements, skincare, and hair care solutions designed for the unique needs of women navigating midlife and hormonal transitions.

Dr. Spencer’s work integrates medicine, prevention, and wellness to help women live healthier, more vibrant lives at every stage.

Perimenopause Wellness Hub
Expert Guidance on Weight Gain, Metabolism, Skin, Hair, Sleep, and Women’s Health in Midlife by April Spencer, M.D.
doctor typing notes into laptop for perimenopause issues
Explore the Doctor’s Note Series

The Doctor’s Note Series provides physician insights on:
• Perimenopause and metabolism
• Hormonal health and midlife wellness
• Breast cancer prevention
• Skin and hair changes during hormonal transitions
• Women’s health and longevity